10/10/25 - #497

Good morning. In today’s edition:

  • Your Coffee May Be Messing With Your Medication

  • Why is Losing Weight So Hard?

  • Does Taking Paracetamol While Pregnant Cause Autism? No, Experts Say

  • Tiny Sugars in the Brain Disrupt Emotional Circuits, Fueling Depression, Study on Mice Finds: IBS Researchers Identify Molecular Pathway in the Mice's Brain That Directly Links Abnormal Sugar Modifications on Proteins to Depressive Behaviors

…and lots more. Have a great day!

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FOOD & NUTRITION

Your Coffee May Be Messing With Your Medication

Do you drink coffee every day? Most Americans do. But your coffee might be getting in the way of your medicine.

Doctors say caffeine can affect how your body uses some drugs. It can make some medicines less helpful or cause stronger side effects like anxiety, shaky hands, or a racing heart.

Here are some medicines that may not mix well with coffee:

  • Antidepressants like fluvoxamine (Luvox) can raise caffeine levels in your body.

  • Blood thinners like warfarin (Coumadin) may lead to more bleeding when mixed with caffeine.

  • Mental health meds like clozapine or olanzapine may build up in your body with caffeine.

  • Asthma drugs like theophylline and caffeine both affect the lungs and heart.

  • Blood pressure pills may not work as well if you drink caffeine.

  • Memory meds like Aricept may not get into the brain as well with coffee.

  • Cold meds like pseudoephedrine and caffeine can make your heart race.

  • Diabetes drugs may work less well if caffeine lowers insulin sensitivity.

  • Bone meds like Fosamax should never be taken with coffee.

  • Some antibiotics like ciprofloxacin can build up with caffeine.

  • Thyroid pills like Synthroid may not work well with coffee.

Good news: You don’t have to give up coffee. Just drink it at least 1 hour before or 2 hours after taking your meds.

Talk to your doctor or pharmacist to be sure.

Disclaimer: This article is for information only and not medical advice.

WEIGHT LOSS

Why is Losing Weight So Hard?

If you’ve ever lost weight, only to gain it back, you’re not alone—and it’s not your fault.

When you lose fat, your body does more than shrink. It also releases hidden toxins. Fat stores harmful chemicals called POPs (Persistent Organic Pollutants). These come from things like pesticides, plastic containers, and skin care products. When you burn fat, these toxins enter your bloodstream. This can stress your liver and kidneys—the body’s natural filters.

As your body gets overwhelmed, it slows your metabolism, messes with your hormones, and makes you feel tired. Cravings go up. And the body does what it’s designed to do: protect itself. It starts storing fat again, often more than before.

This is why “yo-yo” weight loss is so common. It’s not just about willpower. It’s about biology.

But there is a way to help your body through fat loss: support your detox systems.

Here are 3 steps:

  1. Cut the CRAP: Avoid processed Carbs, Rancid oils, Artificial ingredients, and Processed proteins. These put more pressure on your body’s filters.

  2. Help your organs: Drink more water, eat fiber (leafy greens, berries, beans), and move daily to support liver, kidneys, and lymph system.

  3. Feed your liver: Clean protein (like wild fish or pasture-raised eggs) and nutrients like milk thistle, dandelion root, and choline help detoxify.

Weight loss doesn’t have to be a losing battle. If you support your body during fat loss, it won’t need to fight back.

“Disclaimer: This article is for informational purposes only and does not constitute medical advice.”

HEALTH

Does Taking Paracetamol While Pregnant Cause Autism? No, Experts Say

Some people are worried that taking paracetamol (also called acetaminophen) during pregnancy might cause autism. But medical experts say there is no strong proof this is true.

Paracetamol is a common medicine used for pain and fever. It’s found in brands like Tylenol and Panadol. Doctors often recommend it during pregnancy because untreated pain or fever can harm both mother and baby.

Recently, former U.S. President Donald Trump claimed that using paracetamol while pregnant could lead to autism. Health experts strongly disagreed. Groups like the World Health Organization and the European Medicines Agency say there is no solid evidence linking paracetamol to autism.

A large study in Sweden looked at 2.5 million children. It found no link between paracetamol during pregnancy and a child later having autism, ADHD, or learning problems.

Some older studies did raise questions, but many had flaws. For example, they didn’t consider family history. Research shows that genes play a big role in autism, and many cases are inherited from parents.

Experts say that if pregnant women need pain relief, paracetamol is usually the safest choice. Other pain medicines, like aspirin and ibuprofen, can be harmful later in pregnancy.

If you are pregnant, talk to your doctor before taking any medicine. Don’t let fear or rumors guide your choices.

Disclaimer: This article is for general information only. It does not give medical advice. Always follow your doctor’s guidance.

Tiny Sugars in the Brain Disrupt Emotional Circuits, Fueling Depression, Study on Mice Finds: IBS Researchers Identify Molecular Pathway in the Mice's Brain That Directly Links Abnormal Sugar Modifications on Proteins to Depressive Behaviors

Depression is more than just feeling sad. It can affect your energy, sleep, and even how you interact with others. Now, scientists may have found a surprising clue — tiny sugar changes in the brain.

Researchers from the Institute for Basic Science studied mice exposed to long-term stress. They discovered that stress changed how sugar chains (called O-glycans) attach to brain proteins. These changes happened in a brain area called the prefrontal cortex, which helps manage emotions.

One key sugar change is called sialylation, which helps proteins stay stable. In the stressed mice, this process slowed down. The scientists also found that levels of an enzyme called St3gal1, which helps add those sugars, dropped.

Why does this matter? When they lowered this enzyme in healthy mice, the animals showed signs of depression — like less motivation and more anxiety. But when they boosted the enzyme in stressed mice, their behavior improved.

This sugar-related change also affected proteins at brain connections (called synapses), especially a protein called neurexin 2, which helps brain cells “talk” to each other. When sugar chains were off, the emotional circuits in the brain didn’t work right.

This study may help scientists find new ways to treat depression — especially for people who don’t respond to current medications.

“Disclaimer: This article is for informational purposes only. It does not offer medical advice. Always speak with a healthcare provider about mental health concerns.”

A Note From Hem Hero

The information in this health newsletter is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment; always consult your healthcare provider with any questions or concerns you may have regarding your health. The publishers are not responsible for any actions taken by the reader based on the information provided.