12/03/25 - #535

Good morning. In today’s edition:

• Coffee Consumption (4 Cups/day) is Linked to Longer Telomere Lengths – a Marker of Biological Ageing – Among People With Bipolar Disorder and Schizophrenia. The Effect is Comparable to Roughly Five Years Younger Biological Age

• Study Shows That 82% Saw Weight Rebound and Cardiovascular Health Reverse After Withdrawal From Taking GLP-1  Drugs | Cardiometabolic Parameter Change by Weight Regain on Tirzepatide Withdrawal in Adults With Obesity

• Nearly Seven in 10 Medicaid Patients Not Receiving Treatment Within Six Months of an Opioid Use Disorder Diagnosis, Study Finds

• The US Has an "Epilepsy Belt." Poor Sleep, Heat, and Regional Barriers Are Likely Causes

…and lots more. Have a great day!

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FOOD & NUTRITION

Coffee Consumption (4 Cups/day) is Linked to Longer Telomere Lengths – a Marker of Biological Ageing – Among People With Bipolar Disorder and Schizophrenia. The Effect is Comparable to Roughly Five Years Younger Biological Age

A new study from King’s College London found that drinking coffee may help slow signs of aging in people with bipolar disorder and schizophrenia.

The study looked at telomeres. These are small parts at the ends of our DNA that protect our cells. As we age, telomeres get shorter. Shorter telomeres are linked to faster aging and health problems. People with bipolar disorder and schizophrenia often age faster and have shorter lifespans.

Researchers studied 436 adults with serious mental illness. They found that drinking up to four cups of coffee a day was linked to longer telomeres. This was equal to having a biological age about five years younger than people who didn’t drink coffee.

The best results came from drinking three to four cups per day. Drinking more than four cups took away some of the benefits. In fact, people who drank five or more cups had shorter telomeres than those who drank less.

This link stayed strong even after accounting for age, gender, ethnicity, smoking, and medications.

Coffee has both good and bad effects. It may hurt sleep if you drink too much, but in the right amount, it may help slow aging.

More studies are needed to know if coffee truly causes this effect. But for now, this research gives hope that a simple habit—like drinking coffee—might support better health.

Disclaimer: This article is for informational purposes only and does not offer medical advice. Please talk to your doctor before making health changes.

Source: kcl.ac.uk

WEIGHT LOSS

Study Shows That 82% Saw Weight Rebound and Cardiovascular Health Reverse After Withdrawal From Taking GLP-1  Drugs | Cardiometabolic Parameter Change by Weight Regain on Tirzepatide Withdrawal in Adults With Obesity

Many people lose weight and improve their health with GLP-1 drugs like tirzepatide (Zepbound). But a new study shows that most gain back the weight—and lose health benefits—after stopping the drug.

In the study, 670 adults with obesity or excess weight (but no diabetes) took tirzepatide for 36 weeks. Then, half stopped the drug and took a placebo for another 52 weeks. Both groups followed a low-calorie diet and exercise plan.

Researchers focused on 308 people who had lost at least 10% of their body weight. Of those, 82% gained back at least 25% of the lost weight after stopping. Over half gained back 50% or more. As people regained weight, their blood pressure, blood sugar, and cholesterol also got worse.

Only 17% kept off most of the weight, and 4% lost more weight after stopping. It’s not clear why these people did better. The study did not find major differences in age, sex, or health between those who kept the weight off and those who didn’t.

Experts say this shows GLP-1 drugs may need to be used long-term, like blood pressure or diabetes medicine. There isn’t enough data yet on how to stop these drugs safely. Some people may try to slowly reduce their dose or change their diet and exercise.

For now, doctors say patients should see these drugs as a long-term tool—not a quick fix.

Disclaimer: This article is for informational purposes only and is not medical advice. Please talk to your doctor.

Source: arstechnica.com

HEALTH

Nearly Seven in 10 Medicaid Patients Not Receiving Treatment Within Six Months of an Opioid Use Disorder Diagnosis, Study Finds

A new study shows that nearly 7 out of 10 Medicaid patients with opioid addiction do not get medicine-based treatment within six months of being diagnosed. These medicines—like methadone and buprenorphine—can greatly lower the risk of overdose, but many people never get them.

The study looked at over 1 million adults on Medicaid between 2016 and 2019. It found small improvements over time, but most people still went without treatment. Experts say this delay can be deadly.

Black and Hispanic patients were less likely than White patients to get help. Methadone, the most effective medicine, cuts overdose risk by 86%. But it often requires daily visits to a clinic, which is hard for many. The study says giving people the option to take methadone at home could help.

Medicaid is the main insurance for addiction treatment in the U.S. But upcoming budget cuts may make it even harder to get care.

The study’s authors say lawmakers should protect Medicaid and improve access to treatment. They also suggest steps to help people stay in care, like reducing the number of clinic visits needed.

The U.S. is still facing a major opioid crisis. Better access to these medicines could save many lives.

Disclaimer: This article is for informational purposes only and is not medical advice. Always talk to your doctor about your health and treatment options.

Source: newsroom.taylorandfrancisgroup.com

The US Has an "Epilepsy Belt." Poor Sleep, Heat, and Regional Barriers Are Likely Causes

Where you live in the U.S. may raise your risk of epilepsy as you get older. A new study shows that seniors in parts of the South—like Louisiana, East Texas, and Central Oklahoma—have much higher rates of epilepsy. Experts now call this region the “epilepsy belt.”

Researchers looked at Medicare data from people 65 and older. They found big differences in how often epilepsy was diagnosed. In some areas, the rate was 10 times higher than in others.

One key factor was sleep. In places where many adults get less than 7 hours of sleep a night, epilepsy was more common. Poor sleep can cause seizures, and seizures can also disrupt sleep. Sleep problems are more common with age and in places with more stress and poverty.

Heat also played a role. Regions with more very hot days (over 95°F) had more cases. Heat can hurt sleep, raise stroke risk, and limit daily activity—all things that may lead to epilepsy.

The study also found links to lack of exercise, obesity, and fewer people with health insurance. Some areas showed lower rates—especially places with more active jobs like farming and where people recently moved in.

This study looked at regions, not individuals, so it doesn’t prove one thing causes epilepsy. But it shows how local conditions can raise risk.

Improving sleep, access to care, and heat safety may help lower epilepsy rates in older adults.

Disclaimer: This article is for informational purposes only and does not provide medical advice.

Source: zmescience.com

✢ A Note From Hem Hero

The information in this health newsletter is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment; always consult your healthcare provider with any questions or concerns you may have regarding your health. The publishers are not responsible for any actions taken by the reader based on the information provided.